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DHX8 Antibody

  • 货号:
    CSB-PA596171
  • 规格:
    ¥2024
  • 图片:
    • Western blot analysis of extracts from HeLa cells, Jurkat cells and HepG2 cells, using DHX8 antibody.
  • 其他:

产品详情

  • 产品名称:
    Rabbit anti-Homo sapiens (Human) DHX8 Polyclonal antibody
  • Uniprot No.:
    Q14562
  • 基因名:
    DHX8
  • 宿主:
    Rabbit
  • 反应种属:
    Human
  • 免疫原:
    Synthesized peptide derived from internal of Human DHX8.
  • 免疫原种属:
    Homo sapiens (Human)
  • 克隆类型:
    Polyclonal
  • 纯化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA,WB
  • 推荐稀释比:
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    Involved in pre-mRNA splicing as component of the spliceosome. Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome.
  • 基因功能参考文献:
    1. cellular complexes comprising cactin, DHX8 and SRRM2 sustain precise chromosome segregation, genome stability and cell proliferation by allowing faithful splicing of specific pre-mRNAs. PMID: 28062851
    2. structural and functional analysis of C-terminal domain of the spliceosomal helicase Prp22 PMID: 23096351
    3. Preliminary X-ray diffraction analysis of the crystals of the C-terminal domain of the human DExD/H-box protein hPrp22 at 2.1 A resolution, is reported. PMID: 19724143
  • 亚细胞定位:
    Nucleus.
  • 蛋白家族:
    DEAD box helicase family, DEAH subfamily, DDX8/PRP22 sub-subfamily
  • 组织特异性:
    Expressed in skin, cervix and nerve. Also expressed in the brain.
  • 数据库链接:

    HGNC: 2749

    OMIM: 600396

    KEGG: hsa:1659

    STRING: 9606.ENSP00000262415

    UniGene: Hs.463105