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DNASE1L1 Antibody

  • 货号：
    CSB-PA007050GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    P49184
  • 基因名：
    DNASE1L1
  • 别名：
    Deoxyribonuclease I-like 1 antibody; Deoxyribonuclease-1-like 1 antibody; DNAS1L1 antibody; DNase I like 1 antibody; DNase I like muscle specific antibody; DNase I lysosomal like antibody; DNase I-like 1 antibody; DNase X antibody; DNASE1L1 antibody; DNASEX antibody; DNL1L antibody; DNSL1_HUMAN antibody; Muscle specific DNase I like antibody; Muscle-specific DNase I-like antibody; XIB antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human DNASE1L1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. genotyping of all 21 nonsynonymous DNase 1L1 SNPs was performed in 16 populations representing 3 ethnic groups; 2 activity-abolishing and 4 activity-reducing SNPs were confirmed to be functional; may be plausible that a minor allele of 6 SNPs producing a loss-of-function or low-activity variant could serve as a risk factor for disease PMID: 24329527
    2. Yeast two-hybrid screening revealed that DNase X, a glycosylphosphatidyl inositol-anchored mammalian cell-surface protein binds EtpE-C. PMID: 24098122
    3. DNASEX and TKTL1 detection in patient blood is associated with poor disease-free survival rate in oral squamous cell carcinoma. PMID: 24304513
    4. Several SNPs in the deoxyribonuclease I-like 1 (DNase 1L1) and DNase 1L2 were investigated. PMID: 20967767
    5. Genotyping of all the non-synonymous SNPs of was performed in three ethnic groups including six different populations using the PCR-RFLP method newly developed. PMID: 20503202

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  • 亚细胞定位：
    Endoplasmic reticulum.
  • 蛋白家族：
    DNase I family
  • 组织特异性：
    Highest levels in skeletal and cardiac muscles. Detectable in all other tissues tested except brain.
  • 数据库链接：

    HGNC: 2957

    OMIM: 300081

    KEGG: hsa:1774

    STRING: 9606.ENSP00000014935

    UniGene: Hs.401929