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DOCK5 Antibody

  • 货号：
    CSB-PA875689LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) DOCK5 Polyclonal antibody
  • Uniprot No.：
    Q9H7D0
  • 基因名：
    DOCK5
  • 别名：
    DOCK5Dedicator of cytokinesis protein 5 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Dedicator of cytokinesis protein 5 protein (1-200AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，DOCK5 Antibody (CSB-PA875689LA01HU)，的标记方式是Non-conjugated。对于DOCK5 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA875689LB01HU DOCK5 Antibody, HRP conjugated ELISA
    FITC CSB-PA875689LC01HU DOCK5 Antibody, FITC conjugated
    Biotin CSB-PA875689LD01HU DOCK5 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen.
  • 基因功能参考文献：
    1. our work identifies DOCK5 as a key regulator of epithelial invasion and metastasis, and demonstrates that suppression of DOCK5 by GIT2 represents a previously unappreciated mechanism for coordination of Rho and Rac GTPases. PMID: 27669437
    2. the potential role of DOCK5 in human obesity PMID: 22595969
    3. along with DOCK1, DOCK5 is an important mediator of CrkII/CrkL regulation of Caco-2 spreading and migration on collagen IV. PMID: 19004829
  • 亚细胞定位：
    Cytoplasm. Cell membrane.
  • 蛋白家族：
    DOCK family
  • 数据库链接：

    HGNC: 23476

    OMIM: 616904

    KEGG: hsa:80005

    STRING: 9606.ENSP00000276440

    UniGene: Hs.195403