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DPH3 Antibody

  • 货号：
    CSB-PA822214LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) DPH3 Polyclonal antibody
  • Uniprot No.：
    Q96FX2
  • 基因名：
    DPH3
  • 别名：
    DPH3 antibody; DESR1 antibody; ZCSL2DPH3 homolog antibody; CSL-type zinc finger-containing protein 2 antibody; DelGEF-interacting protein 1 antibody; DelGIP1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human DPH3 homolog protein (1-82AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，DPH3 Antibody (CSB-PA822214LA01HU)，的标记方式是Non-conjugated。对于DPH3 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA822214LB01HU DPH3 Antibody, HRP conjugated ELISA
    FITC CSB-PA822214LC01HU DPH3 Antibody, FITC conjugated
    Biotin CSB-PA822214LD01HU DPH3 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Essential for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in elongation factor 2 (EEF2) and which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta).; Down-regulation increases extracellular release of proteoglycans, indicating a possible role in the secretion process. Stimulates binding of GNEFR to SEC5.
  • 基因功能参考文献：
    1. The results from this study show occurrence of frequent somatic non-coding mutations adjacent to a pre-existing binding site for Ets transcription factors within the directional promoter of DPH3 and OXNAD1 genes in three major skin cancers. PMID: 26416425
    2. DelGIP1is a binding partner of deafness locus putative guanine nucleotide exchange factor; downregulation of DelGIP1 induced increased extracellular secretion of proteoglycans indicating a possible role for DelGIP1 in the secretion process PMID: 14980502
    3. Solution structure of human DESR1, a CSL zinc-binding protein. PMID: 18214955
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    DPH3 family
  • 组织特异性：
    Widely expressed with highest levels in small intestine, spleen, thymus, heart, liver and lung.
  • 数据库链接：

    HGNC: 27717

    OMIM: 608959

    KEGG: hsa:285381

    STRING: 9606.ENSP00000419599

    UniGene: Hs.388087