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DYNLL2 Antibody

  • 货号：
    CSB-PA007308
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q96FJ2
  • 基因名：
    DYNLL2
  • 别名：
    8 kDa dynein light chain b antibody; C87222 antibody; cytoplasmic antibody; Dlc2 antibody; DLC8b antibody; DNCL1B antibody; DYL2_HUMAN antibody; Dynein light chain 2 antibody; Dynein light chain 2; cytoplasmic antibody; Dynein light chain LC8 type 2 antibody; Dynein light chain LC8-type 2 antibody; Dynll2 antibody; MGC17810 antibody; MGC72334 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human Dynein LC 2.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
  • 基因功能参考文献：
    1. The DYNLL2 binding region, located in an intrinsically disordered domain of the myo5a tail, has a nascent helical character. PMID: 25312846
    2. the thermodynamic and kinetic fine-tuning of binding of various ligands to DYNLL could have physiological relevance in its interaction network. PMID: 20889982
  • 亚细胞定位：
    Cytoplasm, cytoskeleton.
  • 蛋白家族：
    Dynein light chain family
  • 数据库链接：

    HGNC: 24596

    OMIM: 608942

    KEGG: hsa:140735

    STRING: 9606.ENSP00000240343

    UniGene: Hs.720595