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DYNLRB2 Antibody

  • 中文名称：
    DYNLRB2兔多克隆抗体
  • 货号：
    CSB-PA060270
  • 规格：
    ￥880
  • 其他：

产品详情

  • Uniprot No.：
    Q8TF09
  • 基因名：
    DYNLRB2
  • 别名：
    DYNLRB2 antibody; DNCL2B antibody; DNLC2B antibody; ROBLD2Dynein light chain roadblock-type 2 antibody; Dynein light chain 2B antibody; cytoplasmic antibody; Roadblock domain-containing protein 2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Dynein LC 2B.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    IHC, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:10000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
  • 基因功能参考文献：
    1. Among the total 68 liver cancer samples tested, DNLC2B was down-regulated in 28 cases. PMID: 11750132
    2. Findings indicate that km23-2 (DYNLRB2) is required for Smad3-dependent TGFbeta signaling. Km23-2 has functions in TGFbeta signaling that are distinct from those for km23-1 (DYNLRB1). PMID: 19711352
  • 亚细胞定位：
    Cytoplasm, cytoskeleton.
  • 蛋白家族：
    GAMAD family
  • 组织特异性：
    High expression in heart, brain, placenta, skeletal muscle, prostate and small intestine; moderate in kidney, pancreas, spleen, testis, ovary and colon; low in lung, liver, thymus and leukocyte.
  • 数据库链接：

    HGNC: 15467

    OMIM: 607168

    KEGG: hsa:83657

    STRING: 9606.ENSP00000302936

    UniGene: Hs.98849