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Defb14 Antibody

  • 货号：
    CSB-PA749254HA01MO
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: Defb14 antibody at 12µg/ml + Rat liver tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 8 kDa
      Observed band size: 8 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Mus musculus (Mouse) Defb14 Polyclonal antibody
  • Uniprot No.：
    Q7TNV9
  • 基因名：
    Defb14
  • 别名：
    Defb14 antibody; Beta-defensin 14 antibody; BD-14 antibody; mBD-14 antibody; Defensin antibody; beta 14 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Mouse, Rat
  • 免疫原：
    Recombinant Mouse Beta-defensin 14 protein (23-67AA)
  • 免疫原种属：
    Mus musculus (Mouse)
  • 标记方式：
    Non-conjugated

    本页面中的产品，Defb14 Antibody (CSB-PA749254HA01MO)，的标记方式是Non-conjugated。对于Defb14 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA749254HB01MO Defb14 Antibody, HRP conjugated ELISA
    FITC CSB-PA749254HC01MO Defb14 Antibody, FITC conjugated
    Biotin CSB-PA749254HD01MO Defb14 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Has antibacterial activity.
  • 基因功能参考文献：
    1. this work demonstrates that mouse beta-defensin-14 can promote the maturation of dendritic cells in which TLR-4 is possibly involved PMID: 29253819
    2. This study indicated that the potential antibacterial role of increased MBD-14 in the osteomyelitis mouse model. PMID: 24489798
    3. BD14 expression by tumor-infiltrating host cells results in chemoattraction of CCR6-positive B220-positive lymphocytes, which in turn initiates a proangiogenic pathway leading to enhanced angiogenesis and organized tumor tissue development. PMID: 22504651
    4. Murine beta-defensin-14, like ultraviolet radiation (UVR), can shift surface marker expression of CD4+CD25- T cells toward a regulatory (Treg) phenotype but does not appear to play a major role in UVR-induced immunosuppression. PMID: 22174455
    5. beta-defensin 4 and 14 contribute to the innate and adaptive immune response in their role as chemoattractants PMID: 20483750
    6. both hBD3 and mBD14 were chemotactic for freshly isolated mouse resident peritoneal cells. Thus, mBD14, based on structural and functional similarities, appears to be an orthologue of hBD3. PMID: 18167348
    7. chemoattractant and antimicrobial activities of beta-defensins can be separated, and both of these functions are independent of intramolecular disulfide bonds PMID: 18180295

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Beta-defensin family
  • 数据库链接：

    KEGG: mmu:244332

    STRING: 10090.ENSMUSP00000062781

    UniGene: Mm.358923