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Delta-ctenitoxin-Pn1a Antibody

  • 货号：
    CSB-PA349440HA01EUV
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Phoneutria nigriventer N/A Polyclonal antibody
  • Uniprot No.：
    P59368
  • 基因名：
    N/A
  • 别名：
    antibody; Delta-ctenitoxin-Pn1a antibody; Delta-CNTX-Pn1a antibody; Insecticidal neurotoxin Tx4(6-1) antibody; PnTx4(6-1) antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Phoneutria nigriventer
  • 免疫原：
    Recombinant Phoneutria nigriventer Delta-ctenitoxin-Pn1a protein (35-82AA)
  • 免疫原种属：
    Phoneutria nigriventer
  • 标记方式：
    Non-conjugated

    本页面中的产品，Delta-ctenitoxin-Pn1a Antibody (CSB-PA349440HA01EUV)，的标记方式是Non-conjugated。对于Delta-ctenitoxin-Pn1a Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA349440HB01EUV Delta-ctenitoxin-Pn1a Antibody, HRP conjugated ELISA
    FITC CSB-PA349440HC01EUV Delta-ctenitoxin-Pn1a Antibody, FITC conjugated
    Biotin CSB-PA349440HD01EUV Delta-ctenitoxin-Pn1a Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    This neurotoxin binds at site 3 of insect voltage-activated sodium channels (Nav) and prolongs evoked axonal action potentials by a slowing down of sodium current inactivation. The toxin also inhibits glutamate uptake from rat brain synaptosomes. It reversibly inhibits the N-methyl-D-aspartate (NMDA)-subtype of ionotropic glutamate receptor (GRIN). In addition, the toxin shows antinociceptive effect in all rat pain models tested (inflammatory, neuropathic and nociceptive). The antinociceptive effect is partially blocked when selective antagonists of both mu- and delta-opioid receptors are administered, revealing that the antinociceptive effect of the toxin involves both opiod and cannabinoid endogenous systems. In vivo, it is highly toxic to house fly (Musca domestica), toxic to cockroach, but has no effect when intracerebroventricularly injected into mice.
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Spider toxin Tx2 family
  • 组织特异性：
    Expressed by the venom gland.