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EAPP Antibody

  • 货号：
    CSB-PA007353LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: 293 whole cell lysate
      All lanes: EAPP antibody at 3.2µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 33 kDa
      Observed band size: 33 kDa
    • IHC image of CSB-PA007353LA01HU diluted at 1:400 and staining in paraffin-embedded human skeletal muscle tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) EAPP Polyclonal antibody
  • Uniprot No.：
    Q56P03
  • 基因名：
    EAPP
  • 别名：
    1810011O16Rik antibody; BM-036 antibody; BM036 antibody; C14orf11 antibody; E2F-associated phosphoprotein antibody; EAPP antibody; EAPP_HUMAN antibody; RGD1309624 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human E2F-associated phosphoprotein protein (1-285AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，EAPP Antibody (CSB-PA007353LA01HU)，的标记方式是Non-conjugated。对于EAPP Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA007353LB01HU EAPP Antibody, HRP conjugated ELISA
    FITC CSB-PA007353LC01HU EAPP Antibody, FITC conjugated
    Biotin CSB-PA007353LD01HU EAPP Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:200-1:500
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May play an important role in the fine-tuning of both major E2F1 activities, the regulation of the cell-cycle and the induction of apoptosis. Promotes S-phase entry, and inhibits p14(ARP) expression.
  • 基因功能参考文献：
    1. Independently of EAPP, E2F1 also increases the activity of the MDR1 promoter. PMID: 23542036
    2. results indicate that the level of EAPP is critical for cellular homeostasis PMID: 21258403
    3. EAPP modulates E2F-regulated transcription, stimulates proliferation, and may be involved in the malignant transformation of cells. PMID: 15716352
    4. Regulation of the EAPP promoter by GC-box binding proteins is reported. PMID: 18588995
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 组织特异性：
    Ubiquitously expressed. Highest levels in heart, placenta, skeletal muscle and pancreas. Lower levels in brain, lung and kidney. In the brain, expressed in all regions with high levels in the cerebellum and cerebral cortex. Expressed in COS1 and transform
  • 数据库链接：

    HGNC: 19312

    OMIM: 609486

    KEGG: hsa:55837

    STRING: 9606.ENSP00000250454

    UniGene: Hs.433269