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EIF1 Antibody

  • 货号：
    CSB-PA022391
  • 规格：
    ￥2024
  • 图片：
    • Western blot analysis of extracts from whole fruit fly(drosophila melanogaster) tissue lysate using Eif1 Antibody.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) EIF1 Polyclonal antibody
  • Uniprot No.：
    P41567
  • 基因名：
    EIF1
  • 宿主：
    Rabbit
  • 反应种属：
    Drosophila melanogaster
  • 免疫原：
    Peptide sequence around aa. 4~8 (Q-N-L-N-T) derived from Drosophila Eif1
  • 免疫原种属：
    Homo sapiens (Human)
  • 克隆类型：
    Polyclonal
  • 纯化方式：
    Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:1000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Necessary for scanning and involved in initiation site selection. Promotes the assembly of 48S ribosomal complexes at the authentic initiation codon of a conventional capped mRNA.
  • 基因功能参考文献：
    1. Anti-Sui1 could be utilized as a supplementary serological marker. PMID: 26386724
    2. eIF1A is a novel component of the Ago2-centred RNA-induced silencing complexes (RISCs) and augments Ago2-dependent RNAi and miRNA biogenesis. PMID: 26018492
    3. eEF4GI shares this activity and also interacts with eIF1. PMID: 25738462
    4. eIF1, eIF1A, eIF3j, and the eIF2-GTP-Met-tRNAi ternary complex stably bind to the 43 S preinitiation complex PMID: 25246524
    5. Coordinated movements of eukaryotic translation initiation factors eIF1, eIF1A, and eIF5 trigger phosphate release from eIF2 in response to start codon recognition by the ribosomal preinitiation complex PMID: 23293029
    6. This study provides mechanistic insight into the role of eIF5-carboxyl terminal domain's dynamic interplay with eIF1 and eIF2beta. PMID: 22813744
    7. show that the stringency of start codon selection (preferential utilization of optimal start sites) is increased to a surprising degree by overexpressing eIF1 PMID: 20921384

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  • 蛋白家族：
    SUI1 family
  • 数据库链接：

    HGNC: 3249

    KEGG: hsa:10209

    STRING: 9606.ENSP00000419449

    UniGene: Hs.150580