EIF2B3 Antibody
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货号:CSB-PA912439
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规格:¥2024
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图片:
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其他:
产品详情
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产品名称:Rabbit anti-Homo sapiens (Human) EIF2B3 Polyclonal antibody
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Uniprot No.:Q9NR50
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基因名:EIF2B3
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宿主:Rabbit
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反应种属:Human,Mouse
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免疫原:Synthesized peptide derived from Internal of Human EIF2B3.
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免疫原种属:Homo sapiens (Human)
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克隆类型:Polyclonal
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纯化方式:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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浓度:It differs from different batches. Please contact us to confirm it.
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产品提供形式:Liquid
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应用范围:ELISA,WB
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推荐稀释比:
Application Recommended Dilution WB 1:500-1:3000 -
Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
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基因功能参考文献:
- To determine the tolerance differences to ERS, cell viability and apoptosis rates were detected in oligodendrocyte cell lines transfected with EIF2B3-c.1037T>C or the wild type. We confirmed that oligodendrocytes with mutant EIF2B3 was less tolerant to ERS than the wild type, with decreased cell viability and increased apoptosis rates. PMID: 26625702
- Results show significant higher incidence of Chinese patients with EIF2B3 mutations compared with Caucasian patients. The c.1037T>C in EIF2B3 was confirmed to be a founder mutation in Chinese explaining the genotypic differences between ethnicities. PMID: 25761052
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相关疾病:Leukodystrophy with vanishing white matter (VWM)
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蛋白家族:EIF-2B gamma/epsilon subunits family
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数据库链接:
HGNC: 3259
OMIM: 603896
KEGG: hsa:8891
STRING: 9606.ENSP00000353575
UniGene: Hs.533549
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