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ELAVL2 Antibody

  • 货号：
    CSB-PA007593LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: ELAVL2 antibody at 2µg/ml + Mouse brain tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 40, 39 kDa
      Observed band size: 40 kDa
    • Immunohistochemistry analysis of human brain tissue using CSB-PA007593LA01HU at dilution of 1:100
    • Immunohistochemistry analysis of human colon cancer using CSB-PA007593LA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA007593LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
    • Immunofluorescent analysis of PC-3 cells using CSB-PA007593LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ELAVL2 Polyclonal antibody
  • Uniprot No.：
    Q12926
  • 基因名：
    ELAVL2
  • 别名：
    ELAV like neuron specific RNA binding protein 2 antibody; ELAV like Neuronal Protein 1 antibody; ELAV like Protein 2 antibody; ELAV-like neuronal protein 1 antibody; ELAV-like protein 2 antibody; ELAV2_HUMAN antibody; ELAVL2 antibody; HEL-N1 antibody; HELN1 antibody; HU Antigen B antibody; Hu-antigen B antibody; HuB antibody; Nervous System Specific RNA Binding Protein MelN1 antibody; Nervous system-specific RNA-binding protein Hel-N1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human ELAV-like protein 2 protein (4-356AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，ELAVL2 Antibody (CSB-PA007593LA01HU)，的标记方式是Non-conjugated。对于ELAVL2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA007593LB01HU ELAVL2 Antibody, HRP conjugated ELISA
    FITC CSB-PA007593LC01HU ELAVL2 Antibody, FITC conjugated
    Biotin CSB-PA007593LD01HU ELAVL2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    RNA-binding protein that binds to the 3' untranslated region (3'UTR) of target mRNAs. Seems to recognize a GAAA motif. Can bind to its own 3'UTR, the FOS 3'UTR and the ID 3'UTR.
  • 基因功能参考文献：
    1. ELAVL2-regulated co-expression networks are also enriched for neurodevelopmental and synaptic genes, and include genes with human-specific patterns of expression in the frontal pole. Together, these data suggest that ELAVL2 regulation of transcript expression is critical for neuronal function and clinically relevant to autism PMID: 27260404
    2. The 17 proteins that interact with 10 or more other proteins (P < 0.05, FDR < 0.05) were identified as the hub proteins. PMID: 26366417
    3. Tests for gene-environment interaction between these 33 genes and maternal smoking found evidence for interaction with two additional genes: GRID2 and ELAVL2 among European mothers PMID: 23512105
    4. the mutually antagonistic action of two RNA-binding proteins, Hu and hnRNP K, control the timing of the switch from proliferation to neuronal differentiation through the post-transcriptional regulation of p21 mRNA PMID: 15671036
    5. increased level of mRNA transcripts detected in Small Cell Lung Cancer patients PMID: 18607064

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  • 蛋白家族：
    RRM elav family
  • 组织特异性：
    Brain; neural-specific.
  • 数据库链接：

    HGNC: 3313

    OMIM: 601673

    KEGG: hsa:1993

    STRING: 9606.ENSP00000369460

    UniGene: Hs.166109