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ELP2 Antibody

  • 货号：
    CSB-PA944356
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA944356(ELP2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA944356(ELP2 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    Q6IA86
  • 基因名：
    ELP2
  • 别名：
    AU023723 antibody; Elongation protein 2 homolog (S. cerevisiae) antibody; Elongator acetyltransferase complex subunit 2 antibody; Elongator complex protein 2 antibody; elongator protein 2 antibody; ELP2 antibody; ELP2_HUMAN antibody; Epl2 antibody; FLJ10879 antibody; SHINC 2 antibody; SHINC-2 antibody; SHINC2 antibody; signal transducer and activator of transcription 3 interacting protein 1 antibody; signal transducer and activator of transcription interacting protein 1 antibody; STAT3 interacting protein 1 antibody; Stat3 interacting protein antibody; STAT3-interacting protein 1 antibody; STATIP 1 antibody; STATIP1 antibody; STATIP1 protein antibody; StIP antibody; StIP1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Rat
  • 免疫原：
    Fusion protein of Human ELP2
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
  • 基因功能参考文献：
    1. ELP2 mutation is implicated in severe intellectual disability, spastic diplegia, and self-injurious behavior described in two brothers. PMID: 25847581
    2. Studied the possible relationship between STATIP1, STAT3 and CML resistance. PMID: 25417721
    3. Elp2 and STAT-3 mediate, at least in part, the stimulation of Hsp70 expression by 4PBA. PMID: 22069317
  • 相关疾病：
    Mental retardation, autosomal recessive 58 (MRT58)
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    WD repeat ELP2 family
  • 数据库链接：

    HGNC: 18248

    OMIM: 616054

    KEGG: hsa:55250

    UniGene: Hs.606040