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ENY2 Antibody

  • 货号：
    CSB-PA889067LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ENY2 Polyclonal antibody
  • Uniprot No.：
    Q9NPA8
  • 基因名：
    ENY2
  • 别名：
    1810057B09Rik antibody; 6720481I12 antibody; DC6 antibody; e(y)2 antibody; Enhancer of yellow 2 transcription factor homolog antibody; eny2 antibody; ENY2_HUMAN antibody; Ey2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Transcription and mRNA export factor ENY2 protein (1-101AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，ENY2 Antibody (CSB-PA889067LA01HU)，的标记方式是Non-conjugated。对于ENY2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA889067LB01HU ENY2 Antibody, HRP conjugated ELISA
    FITC CSB-PA889067LC01HU ENY2 Antibody, FITC conjugated
    Biotin CSB-PA889067LD01HU ENY2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores.
  • 基因功能参考文献：
    1. ATXN7L3 and ENY2 orchestrate activities of multiple deubiquitinating enzymes, including USP27x and USP51, and that imbalances in these activities likely potentiate human diseases including cancer. PMID: 27132940
    2. ATXN7L3, USP22, & ENY2 are required cofactors for full transcriptional activity by nuclear receptors. The deubiquitinase activity of TFTC/STAGA HAT counteracts heterochromatin silencing & is a positive cofactor for in vivo nuclear receptor activation. PMID: 18206972
  • 亚细胞定位：
    Nucleus, nucleoplasm.
  • 蛋白家族：
    ENY2 family
  • 数据库链接：

    HGNC: 24449

    KEGG: hsa:56943

    STRING: 9606.ENSP00000429986

    UniGene: Hs.492555