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ETV2 Antibody

  • 中文名称：
    ETV2兔多克隆抗体
  • 货号：
    CSB-PA007855LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunofluorescence staining of HepG2 cells with CSB-PA007855LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ETV2 Polyclonal antibody
  • Uniprot No.：
    O00321
  • 基因名：
    ETV2
  • 别名：
    ETV2 antibody; ER71 antibody; ETSRP71ETS translocation variant 2 antibody; Ets-related protein 71 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human ETS translocation variant 2 protein (74-201AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，ETV2 Antibody (CSB-PA007855LA01HU)，的标记方式是Non-conjugated。对于ETV2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA007855LB01HU ETV2 Antibody, HRP conjugated ELISA
    FITC CSB-PA007855LC01HU ETV2 Antibody, FITC conjugated
    Biotin CSB-PA007855LD01HU ETV2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.
  • 基因功能参考文献：
    1. REVIEW. the interplay among the ETS transcription factor ETV2, vascular endothelial growth factor, and its receptor VEGFR2/FLK1 is essential for hematopoietic and vascular development. Emerging studies also support the role of these three factors and possible interplay in hematopoietic and vascular regeneration. PMID: 28026128
    2. Single-factor ETV2 transduction successfully reprogrammed dermal fibroblasts into functional EPCs. PMID: 27488544
    3. ETV2 alone can directly reprogram postnatal cells to functional, mature endothelial cells. PMID: 28003219
    4. ets variant 2 (ETV2) alone directly converts primary human adult skin fibroblasts into functional vascular endothelial cells. PMID: 25540418
    5. identify human Etv2/ER71 and mouse ER71 proteins as functional orthologs of Etsrp PMID: 18270322

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    ETS family
  • 数据库链接：

    HGNC: 3491

    OMIM: 609358

    KEGG: hsa:2116

    STRING: 9606.ENSP00000384524

    UniGene: Hs.194061