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FAM3A Antibody

  • 货号：
    CSB-PA938413
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using CSB-PA938413(FAM3A Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 12%SDS-PAGE, Lysate: 50 μg, Lane: Human fetal brain tissue, Primary antibody: CSB-PA938413(FAM3A Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
  • 其他：

产品详情

  • Uniprot No.：
    P98173
  • 基因名：
    FAM3A
  • 别名：
    2-19 antibody; 2.19 antibody; Cytokine-like protein 2-19 antibody; DLD antibody; DXS560S antibody; FAM3A antibody; FAM3A_HUMAN antibody; family with sequence similarity 3; member A antibody; Protein FAM3A antibody; XAP 7 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human FAM3A
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    WB 1:200-1:1000
    IHC 1:15-1:50
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May act as a defensin against invading fungal microorganisms.
  • 基因功能参考文献：
    1. These results suggest that C/EBPbeta plays an important role in regulating FAM3A promoter activity and FAM3A inhibits adipocyte differentiation. PMID: 27688071
    2. In the present study, we report a putative human homologue of the antimicrobial Drosophila-derived drosomycin, designated drosomycin-like defensin (DLD), with specific antifungal activity. PMID: 18212107
    3. FAM3A plays crucial roles in the regulation of glucose and lipid metabolism in the liver, where it activates the PI3K-Akt signaling pathway by way of a Ca(2+) /CaM-dependent mechanism PMID: 24806753
    4. Upregulation of FAM3A by PPARgamma activation is correlated with increased pAkt level in liver cells PMID: 23562554
    5. Expressed prominently in the vascular endothelium, particularly capillaries, also in islets of Langerhans. PMID: 12160727

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  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    FAM3 family
  • 组织特异性：
    In similar amounts in testis, pancreas, adrenal, placenta, brain, fetal brain, liver, kidney, skeletal muscle and heart.
  • 数据库链接：

    HGNC: 13749

    OMIM: 300492

    KEGG: hsa:60343

    STRING: 9606.ENSP00000352955

    UniGene: Hs.289108