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FARP2 Antibody

  • 货号：
    CSB-PA002536
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of HuvEc cells using FIR Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    O94887
  • 基因名：
  • 别名：
    FARP2 antibody; FARP2_HUMAN antibody; FERM antibody; FERM domain including RhoGEF antibody; FERM; RhoGEF and pleckstrin domain protein 2 antibody; FERM; RhoGEF and pleckstrin domain-containing protein 2 antibody; FGD1 related Cdc42 GEF antibody; FIR antibody; FRG antibody; KIAA0793 antibody; PH domain-containing family C member 3 antibody; Pleckstrin homology domain-containing family C member 3 antibody; PLEKHC3 antibody; RhoGEF and pleckstrin domain protein 2 antibody; RhoGEF and pleckstrin domain-containing protein 2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human FIR.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IF, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion.
  • 基因功能参考文献：
    1. FRG is a member of Cdc42-GEF and plays an important role in the signaling pathway downstream of G protein-coupled receptors PMID: 12771149
  • 数据库链接：

    HGNC: 16460

    OMIM: 617586

    KEGG: hsa:9855

    STRING: 9606.ENSP00000264042

    UniGene: Hs.726316