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FAT3 Antibody

  • 货号：
    CSB-PA068600
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA068600(FAT3 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CSB-PA068600(FAT3 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

产品详情

  • 产品描述：

    Immunization of rabbits with the synthesized peptide of human FAT3 protein yields the anti-serum, which further undergoes antigen affinity purification to get the FAT3 antibody. This FAT3 antibody is a polyclonal antibody and exists as an unconjugated IgG. It can cross-react with human, mouse, and rat FAT3 protein. Validations of this antibody in ELISA and IHC assays have been tested. The target protein FAT3 plays an important role in axon fasciculation and regulation of the extracellular space surrounding axons during embryonic development.

  • Uniprot No.：
    Q8TDW7
  • 基因名：
  • 别名：
    Cadherin family member 15 antibody; CDHF15 antibody; CDHR10 antibody; FAT tumor suppressor homolog 3 antibody; Fat3 antibody; FAT3_HUMAN antibody; hFat3 antibody; KIAA1989 antibody; Protocadherin Fat 3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthetic peptide of Human FAT3
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May play a role in the interactions between neurites derived from specific subsets of neurons during development.
  • 基因功能参考文献：
    1. For Fat3, the Kif5-ID is regulated by alternative splicing, and the timecourse of splicing suggests that the distribution of Fat3 may switch between early and later stages of retinal development. In contrast, P75NTR binding to Kif5B is enhanced by tyrosine phosphorylation and thus has the potential to be dynamically regulated on a more rapid time scale PMID: 27788242
  • 亚细胞定位：
    Membrane; Single-pass type I membrane protein.
  • 组织特异性：
    Expressed in ES cells, primitive neuroectoderm, fetal brain, infant brain, adult neural tissues and prostate.
  • 数据库链接：

    HGNC: 23112

    OMIM: 612483

    KEGG: hsa:120114

    STRING: 9606.ENSP00000298047

    UniGene: Hs.98523