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FGF16 Antibody

  • 货号：
    CSB-PA005775
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of K562 cells using FGF-16 Polyclonal Antibody.
  • 其他：

产品详情

  • Uniprot No.：
    O43320
  • 基因名：
  • 别名：
    FGF 16 antibody; FGF-16 antibody; Fgf16 antibody; FGF16_HUMAN antibody; Fibroblast growth factor 16 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human FGF-16.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation, and is required for normal cardiomyocyte proliferation and heart development.
  • 基因功能参考文献：
    1. Experiments demonstrated FGF16 could promote proliferation of NCL-H460 cells by activating Akt, Erk1/2, and p38 MAPK signaling, whereas JNK had no significant effect. PMID: 28409700
    2. Identification of an FGF16 mutation in metacarpal 4-5 fusion. PMID: 24878828
    3. impaired FGF16 function may also be responsible for connective tissue symptoms in MF4 patients. PMID: 24706454
    4. Fgf-16 gene is a target for NF-kappaB activation in the postnatal heart. PMID: 20097674
    5. HUVEC clearly demonstrated chemotaxis towards FGF16. FGF16 enhanced cell migration in response to mechanical damage & failed to induce endothelial cell proliferation or sprouting in a three-dimensional in vitro angiogenesis assay. PMID: 16756958

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  • 相关疾病：
    Metacarpal 4-5 fusion (MF4)
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Heparin-binding growth factors family
  • 数据库链接：

    HGNC: 3672

    OMIM: 300827

    KEGG: hsa:8823

    STRING: 9606.ENSP00000399324

    UniGene: Hs.666364