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FGFR1OP2 Antibody

  • 货号：
    CSB-PA008644LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: FGFR1OP2 antibody at 6µg/ml
      Lane 1: Mouse gonadal tissue
      Lane 2: Human placenta tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 30, 25, 21 kDa
      Observed band size: 30 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) FGFR1OP2 Polyclonal antibody
  • Uniprot No.：
    Q9NVK5
  • 基因名：
    FGFR1OP2
  • 别名：
    DKFZp564O1863 antibody; FGFR1 oncogene partner 2 antibody; FGFR1OP2 antibody; FGOP2_HUMAN antibody; Fibroblast growth factor receptor 1 oncogene partner 2 antibody; HSPC123 antibody; HSPC123 like antibody; WIT3.0 antibody; Wound inducible transcript 3.0 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human FGFR1 oncogene partner 2 protein (1-172AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，FGFR1OP2 Antibody (CSB-PA008644LA01HU)，的标记方式是Non-conjugated。对于FGFR1OP2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA008644LB01HU FGFR1OP2 Antibody, HRP conjugated ELISA
    FITC CSB-PA008644LC01HU FGFR1OP2 Antibody, FITC conjugated
    Biotin CSB-PA008644LD01HU FGFR1OP2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May be involved in wound healing pathway.
  • 基因功能参考文献：
    1. The patient with minor allele of ss518063493 may be associated with excessive atrophy of edentulous mandible whereas the patients with that of rs840869 are not associated in Korean population. PMID: 22880093
    2. patients with the minor allele of rs840869 or rs859024 of FGFR1OP2 were associated with excessive atrophy of edentulous mandible PMID: 21283824
    3. FGFR1OP2/wit3.0 may regulate cell motility and stimulate wound closure. PMID: 19959814
    4. FGFR1OP2 is a new FGFR1 fusion gene involving a chromosomes 12X8 translocation in a 8p11 myeloproliferative syndrome patient. PMID: 15034873
  • 相关疾病：
    A chromosomal aberration involving FGFR1OP2 may be a cause of stem cell myeloproliferative disorder (MPD). Insertion ins(12;8)(p11;p11p22) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T-cell or B-cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion protein FGFR1OP2-FGFR1 may exhibit constitutive kinase activity and be responsible for the transforming activity.
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    SIKE family
  • 组织特异性：
    Expressed in bone marrow, spleen and thymus.
  • 数据库链接：

    HGNC: 23098

    OMIM: 608858

    KEGG: hsa:26127

    STRING: 9606.ENSP00000229395

    UniGene: Hs.591162