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FNDC4 Antibody

  • 货号：
    CSB-PA872504LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) FNDC4 Polyclonal antibody
  • Uniprot No.：
    Q9H6D8
  • 基因名：
    FNDC4
  • 别名：
    Fibronectin type III domain containing 4 antibody; Fibronectin type III domain containing protein 4 antibody; Fibronectin type III domain-containing protein 4 antibody; Fibronectin type III repeat containing protein 1 antibody; Fibronectin type III repeat-containing protein 1 antibody; FLJ22362 antibody; FNDC 4 antibody; FNDC4 antibody; FNDC4_HUMAN antibody; FRCP 1 antibody; FRCP1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Fibronectin type III domain-containing protein 4 protein (45-167AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，FNDC4 Antibody (CSB-PA872504LA01HU)，的标记方式是Non-conjugated。对于FNDC4 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA872504LB01HU FNDC4 Antibody, HRP conjugated ELISA
    FITC CSB-PA872504LC01HU FNDC4 Antibody, FITC conjugated
    Biotin CSB-PA872504LD01HU FNDC4 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro-inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis.
  • 基因功能参考文献：
    1. FNDC4 as a factor with direct therapeutic potential in inflammatory bowel disease and possibly other inflammatory diseases. PMID: 27066907
    2. Reports the cloning, expression and subcellular localization of the related mouse protein. PMID: 12384288
  • 亚细胞定位：
    Membrane; Single-pass type I membrane protein. Secreted.
  • 组织特异性：
    Up-regulated in colon cells of patients with inflammatory bowel disease (IBD).
  • 数据库链接：

    HGNC: 20239

    OMIM: 611905

    KEGG: hsa:64838

    STRING: 9606.ENSP00000264703

    UniGene: Hs.27836