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FSD1 Antibody

  • 货号：
    CSB-PA861136LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • IHC image of CSB-PA861136LA01HU diluted at 1:500 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA861136LA01HU diluted at 1:500 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) FSD1 Polyclonal antibody
  • Uniprot No.：
    Q9BTV5
  • 基因名：
    FSD1
  • 别名：
    Fibronectin type 3 and SPRY (spla; ryanodine) domain containing (with coiled-coil motif) 1 antibody; Fibronectin type 3 and SPRY domain containing 1 antibody; Fibronectin type III and SPRY domain containing 1 antibody; Fibronectin type III and SPRY domain-containing protein 1 antibody; Fibronectin type III and SPRY domains containing protein 1 antibody; FSD1 antibody; FSD1_HUMAN antibody; GLFND antibody; MGC3213 antibody; MGC58341 antibody; Microtubule-associated protein GLFND antibody; MID1-related protein 1 antibody; midline 1-related protein 1 antibody; MIR1 antibody; VLP27 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Fibronectin type III and SPRY domain-containing protein 1 protein (251-370AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，FSD1 Antibody (CSB-PA861136LA01HU)，的标记方式是Non-conjugated。对于FSD1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA861136LB01HU FSD1 Antibody, HRP conjugated ELISA
    FITC CSB-PA861136LC01HU FSD1 Antibody, FITC conjugated
    Biotin CSB-PA861136LD01HU FSD1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:500-1:1000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May be involved in microtubule organization and stabilization.
  • 基因功能参考文献：
    1. Overexpression of miR-1 mimics significantly decreased tumor glycolysis, including lactate production and glucose uptake, and cell proliferation, and these effects were reversed by ectopic expression of Smad3. PMID: 28471448
    2. These regulatory mechanisms of miR-1 expression could help us to understand the functions of altered miR-1 expression. PMID: 27923712
    3. Taken together, our findings established a tumor suppressive role for miR-1 in the progression of ccRCC by targeting CDK4, CDK6, Caprin1 and Slug and suggested miR-1 can be served as a novel potential therapeutic target for ccRCC. PMID: 26036633
    4. Data report the identification of MIR1, a protein with microtubule-binding activity which is located at the centrosome and is related to MID1/midin. [MIR1] PMID: 12154070
  • 亚细胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm. Cleavage furrow. Note=Cell-cycle-dependent association with the centrosome. Colocalizes with a subpopulation of microtubules. Does not associates with microtubules during mitosis but reassociates with microtubules during cytokinesis. Localizes to the central portions of a small subset of microtubules in interphase cells and a subpopulation of microtubules in the cleavage furrow, not present in the mitotic spindle.
  • 组织特异性：
    Highly expressed in brain tissues, including cerebellum, cerebral cortex, medulla, occipital pole, frontal lobe, temporal lobe and putamen. Lower expression in spinal chord.
  • 数据库链接：

    HGNC: 13745

    OMIM: 609828

    KEGG: hsa:79187

    STRING: 9606.ENSP00000221856

    UniGene: Hs.28144