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FUZ Antibody

  • 货号：
    CSB-PA883593LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry analysis of human melanoma using CSB-PA883593LA01HU at dilution of 1:100
    • Immunofluorescent analysis of A549 cells using CSB-PA883593LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) FUZ Polyclonal antibody
  • Uniprot No.：
    Q9BT04
  • 基因名：
    FUZ
  • 别名：
    FLJ22688 antibody; fuz antibody; FUZZY_HUMAN antibody; Fy antibody; Protein fuzzy homolog antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Protein fuzzy homolog protein (280-404AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，FUZ Antibody (CSB-PA883593LA01HU)，的标记方式是Non-conjugated。对于FUZ Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA883593LB01HU FUZ Antibody, HRP conjugated ELISA
    FITC CSB-PA883593LC01HU FUZ Antibody, FITC conjugated
    Biotin CSB-PA883593LD01HU FUZ Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Probable planar cell polarity effector involved in cilium biogenesis. May regulate protein and membrane transport to the cilium. Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies. May regulate the morphogenesis of hair follicles which depends on functional primary cilia.
  • 基因功能参考文献：
    1. results in vitro show that FUZ is responsible for non-small-cell lung cancer (NSCLC) progression and metastasis, suggesting that FUZ can be a potential therapeutic target for NSCLC. PMID: 29421438
    2. Data propose that mutations in Fuzzy may account for a subset of neural tube defects in humans. PMID: 21840926
  • 亚细胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, cilium basal body.
  • 蛋白家族：
    Fuzzy family
  • 数据库链接：

    HGNC: 26219

    OMIM: 610622

    KEGG: hsa:80199

    STRING: 9606.ENSP00000313309

    UniGene: Hs.288800