G Antibody

Datasheet

产品详情

产品描述：

Immunization of rabbits with the Australian bat lyssavirus (ABLV) glycoprotein (G) produces the anti-serum, which is purified through antigen affinity to get the anti-ABLV G antibody. This G antibody occurs as an IgG. It can react with human samples. And it is available for use in ELISA analysis. The single fusogenic envelope glycoprotein (G), a key determinant of viral neurotropic and neurovirulent properties, mediates the pH-dependent fusion between ABLV and host cells.
Uniprot No.：

Q8JTH0
基因名：

G
别名：

G; Glycoprotein
反应种属：

Human
免疫原：

Human G-CSF-R
免疫原种属：

Homo sapiens (Human)
抗体亚型：

IgG
纯化方式：

Antigen Affinity purified
浓度：

It differs from different batches. Please contact us to confirm it.
保存缓冲液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20oC, Avoid freeze / thaw cycles.
产品提供形式：

Liquid
应用范围：

ELISA
Protocols：

ELISA Protocol
储存条件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
货期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

功能：

Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.
亚细胞定位：

Virion membrane; Single-pass type I membrane protein.
蛋白家族：

Lyssavirus glycoprotein family