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GALM Antibody

  • 货号：
    CSB-PA009200GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q96C23
  • 基因名：
    GALM
  • 别名：
    Aldose 1 epimerase antibody; Aldose 1-epimerase antibody; BLOCK25 antibody; Galactomutarotase antibody; Galactose mutarotase antibody; Galm antibody; GALM_HUMAN antibody; IBD1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human GALM
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Mutarotase that catalyzes the interconversion of beta-D-galactose and alpha-D-galactose during galactose metabolism. Beta-D-galactose is metabolized in the liver into glucose 1-phosphate, the primary metabolic fuel, by the action of four enzymes that constitute the Leloir pathway: GALM, GALK1 (galactokinase), GALT (galactose-1-phosphate uridylyltransferase) and GALE (UDP-galactose-4'-epimerase). Involved in the maintenance of the equilibrium between the beta- and alpha-anomers of galactose, therefore ensuring a sufficient supply of the alpha-anomer for GALK1. Also active on D-glucose although shows a preference for galactose over glucose.
  • 基因功能参考文献：
    1. This study demonistrated that polymorphism in galactose mutarotase (GALM) is associated with serotonin transporter binding potential in the human thalamus. PMID: 21339755
    2. Identification and characterisation of human aldose 1-epimerase. PMID: 12753898
    3. The enzyme is a monomer and has a similar structure to the Lactococcus lactis mutarotase. PMID: 15026423
    4. Gene encodes a functional aldose 1-epimerase (mutarotase). The enzyme exhibits (approx. four-fold) preference for galactose over glucose. Mutation E307A results in no detactable activity. PMID: 12753898
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Aldose epimerase family
  • 数据库链接：

    HGNC: 24063

    OMIM: 137030

    KEGG: hsa:130589

    STRING: 9606.ENSP00000272252

    UniGene: Hs.435012