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GDI2 Antibody

  • 货号：
    CSB-PA005461
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of A549 HT29 K562 mouse kidney mouse lung cells using GDI-2 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    P50395
  • 基因名：
    GDI2
  • 别名：
    GDI-2 antibody; GDI2 antibody; GDIB_HUMAN antibody; GDP dissociation inhibitor 2 antibody; Guanosine diphosphate dissociation inhibitor 2 antibody; Rab GDI beta antibody; Rab GDP dissociation inhibitor beta antibody; RABGDIB antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human GDI-2.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
  • 基因功能参考文献：
    1. Reduction of nucleoside diphosphate kinase B, Rab GDP-dissociation inhibitor beta and histidine triad nucleotide-binding protein in fetal Down syndrome brain. PMID: 11771757
    2. The increased levels of cyclin I and GDI2 found to be associated with pancreatic carcinoma were further confirmed by Western blot analyses in an independent series of serum samples and/or pancreatic juice samples PMID: 17507299
  • 亚细胞定位：
    Cytoplasm. Membrane; Peripheral membrane protein.
  • 蛋白家族：
    Rab GDI family
  • 组织特异性：
    Ubiquitous.
  • 数据库链接：

    HGNC: 4227

    OMIM: 600767

    KEGG: hsa:2665

    STRING: 9606.ENSP00000369538

    UniGene: Hs.299055