Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. GINS4 Antibody

GINS4 Antibody

  • 货号：
    CSB-PA871563LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA871563LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA871563LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) GINS4 Polyclonal antibody
  • Uniprot No.：
    Q9BRT9
  • 基因名：
    GINS4
  • 别名：
    DNA replication complex GINS protein SLD5 antibody; GINS complex subunit 4 (Sld5 homolog) antibody; GINS complex subunit 4 antibody; GINS4 antibody; SLD5 antibody; SLD5 homolog antibody; SLD5 S cerevisiae homolog of antibody; SLD5_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human DNA replication complex GINS protein SLD5 protein (2-223AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，GINS4 Antibody (CSB-PA871563LA01HU)，的标记方式是Non-conjugated。对于GINS4 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA871563LB01HU GINS4 Antibody, HRP conjugated ELISA
    FITC CSB-PA871563LC01HU GINS4 Antibody, FITC conjugated
    Biotin CSB-PA871563LD01HU GINS4 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS4 is important for GINS complex assembly. GINS complex seems to bind preferentially to single-stranded DNA.
  • 基因功能参考文献：
    1. Knockdown of SLD5 using small interfering RNA resulted in reduction of cell growth both in vitro and an in vivo xenograft model. Moreover, we found that high levels of SLD5 in bladder cancer cells result from downregulation of microRNA (miR)-370 that otherwise suppresses its expression. PMID: 27499248
    2. Sld5 a component of GINS complex interacts with SIK1 and recruits it to the sites of DNA replication at the onset of S phase. PMID: 27592030
    3. The C-terminal domains of the Sld5 and Psf1 subunits are connected by linker regions to the core complex, and the C-terminal domain of Sld5 is important for core complex assembly. PMID: 17417653
  • 亚细胞定位：
    Nucleus. Chromosome. Cytoplasm.
  • 蛋白家族：
    GINS4/SLD5 family
  • 数据库链接：

    HGNC: 28226

    OMIM: 610611

    KEGG: hsa:84296

    STRING: 9606.ENSP00000276533

    UniGene: Hs.656996