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GPD2 Antibody

  • 货号：
    CSB-PA437630
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA437630(GPD2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA437630(GPD2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 6%SDS-PAGE,Lysate: 40 μg,Lane 1-3: A172 cells, 231 cells, Hela cells,Primary antibody: CSB-PA437630(GPD2 Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 30 seconds
  • 其他：

产品详情

  • Uniprot No.：
    P43304
  • 基因名：
    GPD2
  • 别名：
    GDH2 antibody; Glycerol 3 phosphate dehydrogenase 2 (mitochondrial) antibody; Glycerol 3 phosphate dehydrogenase 2 antibody; Glycerol 3 phosphate dehydrogenase mitochondrial antibody; Glycerol-3-phosphate dehydrogenase antibody; GPD 2 antibody; GPD M antibody; GPD-M antibody; gpd2 antibody; GPDH M antibody; GPDH-M antibody; GPDM antibody; GPDM_HUMAN antibody; mGPDH antibody; mitochondrial antibody; Mitochondrial glycerophosphate dehydrogenase antibody; mtGPD antibody; OTTHUMP00000162788 antibody; OTTHUMP00000204452 antibody; OTTHUMP00000204453 antibody; OTTHUMP00000204458 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthetic peptide of Human GPD2
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:20-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.
  • 基因功能参考文献：
    1. testis-specific promoter of mitochondrial GPDH PMID: 15456763
    2. Overall, these data demonstrate that mGPDH is involved in maintaining a high rate of glycolysis and is an important site of electron leakage leading to ROS production in prostate cancer cells. PMID: 15967408
    3. the up-regulation of mGPDH, due to a highly glycolytic environment, contributes to the overall increase in ROS generation and may result in the progression of prostate cancer PMID: 17886033
  • 亚细胞定位：
    Mitochondrion.
  • 蛋白家族：
    FAD-dependent glycerol-3-phosphate dehydrogenase family
  • 数据库链接：

    HGNC: 4456

    OMIM: 138430

    KEGG: hsa:2820

    STRING: 9606.ENSP00000308610

    UniGene: Hs.512382