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GTPBP1 Antibody

  • 货号：
    CSB-PA010031LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • IHC image of CSB-PA010031LA01HU diluted at 1:500 and staining in paraffin-embedded human adrenal gland tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of 293 cells with CSB-PA010031LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) GTPBP1 Polyclonal antibody
  • Uniprot No.：
    O00178
  • 基因名：
    GTPBP1
  • 别名：
    G protein 1 antibody; G-protein 1 antibody; GP 1 antibody; GP-1 antibody; GP1 antibody; GTP binding protein 1 antibody; GTP-binding protein 1 antibody; GTPB1_HUMAN antibody; GTPBP1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human GTP-binding protein 1 protein (562-669AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，GTPBP1 Antibody (CSB-PA010031LA01HU)，的标记方式是Non-conjugated。对于GTPBP1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA010031LB01HU GTPBP1 Antibody, HRP conjugated ELISA
    FITC CSB-PA010031LC01HU GTPBP1 Antibody, FITC conjugated
    Biotin CSB-PA010031LD01HU GTPBP1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:500-1:1000
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity.
  • 基因功能参考文献：
    1. GTPBP1 possesses eEF1A-like elongation activity, delivering cognate aminoacyl-transfer RNA to the ribosomal A site in a GTP-dependent manner. It also stimulates exosomal degradation of mRNAs in elongation complexes. PMID: 30108131
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    TRAFAC class translation factor GTPase superfamily, Classic translation factor GTPase family, GTPBP1 subfamily
  • 数据库链接：

    HGNC: 4669

    OMIM: 602245

    KEGG: hsa:9567

    STRING: 9606.ENSP00000216044

    UniGene: Hs.276925