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Gsta1 Antibody

  • 中文名称：
    Gsta1兔多克隆抗体
  • 货号：
    CSB-PA009970HA01MO
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Mouse stomach tissue
      All lanes: Gsta1 antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 26 kDa
      Observed band size: 26 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Mus musculus (Mouse) Gsta1 Polyclonal antibody
  • Uniprot No.：
    P13745
  • 基因名：
    Gsta1
  • 别名：
    Gsta1 antibody; Gsta antibody; Gstya antibody; Glutathione S-transferase A1 antibody; EC 2.5.1.18 antibody; 13-hydroperoxyoctadecadienoate peroxidase antibody; EC 1.11.1.- antibody; Androst-5-ene-3,17-dione isomerase antibody; EC 5.3.3.- antibody; GST class-alpha member 1 antibody; Glutathione S-transferase Ya antibody; Glutathione S-transferase Ya1) [Cleaved into: Glutathione S-transferase A1 antibody; N-terminally processed] antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Mouse
  • 免疫原：
    Recombinant Mouse Glutathione S-transferase A1 protein (2-223AA)
  • 免疫原种属：
    Mus musculus (Mouse)
  • 标记方式：
    Non-conjugated

    本页面中的产品，Gsta1 Antibody (CSB-PA009970HA01MO)，的标记方式是Non-conjugated。对于Gsta1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA009970HB01MO Gsta1 Antibody, HRP conjugated ELISA
    FITC CSB-PA009970HC01MO Gsta1 Antibody, FITC conjugated
    Biotin CSB-PA009970HD01MO Gsta1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds (Probable). Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). It also catalyzes the isomerization of D5-androstene-3,17-dione (AD) into D4-androstene-3,17-dione and may therefore play an important role in hormone biosynthesis. Through its glutathione-dependent peroxidase activity toward the fatty acid hydroperoxide (13S)-hydroperoxy-(9Z,11E)-octadecadienoate/13-HPODE it is also involved in the metabolism of oxidized linoleic acid.
  • 基因功能参考文献：
    1. GSTA1 can be detected at the early stage of low concentration ethanol exposure and that GSTA1 is more sensitive and reliable marker in ethanol-induced hepatic injury. PMID: 27198676
    2. results suggest that GSTA1 can be detected at low concentrations during the early stages of acute hepatic injury and that GSTA1 is a more sensitive and more accurate indicator than ALT PMID: 24964013
    3. Report increased GSTA1 in airways of asthmatic mice. PMID: 23647087
    4. mitochondrial Gsta1 is induced under oxidative stress PMID: 12020353
    5. Exceptional activity of murine glutathione transferase A1-1 against (7R,8S)-dihydroxy-(9S,10R)-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene-induced DNA damage in stably transfected cells PMID: 12557262
    6. This is the first demonstration that heavy metals (mercury, lead and copper) regulate the expression of Gst ya gene through a transcriptional mechanism. PMID: 16243960
    7. Analysis of the expressed luciferase activity indicated that MMA activated the promoter 2.6-fold. MMA (from 1 to 30 mM) dose-dependently increased the promoter activity, which reached a plateau between 6 and 12 hrs. PMID: 19029078
    8. Essential roles of ERKs and p38K in up-regulation of GST A1 expression by Maotai content in human hepatoma cell line Hep3B.It is widely accepted that the consumption of alcohol may lead to hepatic injuries such as hepatic fibrosis and cirrhosis. PMID: 16786188

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  • 蛋白家族：
    GST superfamily, Alpha family
  • 数据库链接：

    KEGG: mmu:14857

    STRING: 10090.ENSMUSP00000096139

    UniGene: Mm.467426