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HAAO Antibody

  • 货号：
    CSB-PA010112GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    P46952
  • 基因名：
    HAAO
  • 别名：
    3 HAO antibody; 3 hydroxyanthranilate 3 4 dioxygenase antibody; 3 hydroxyanthranilate dioxygenase antibody; 3 hydroxyanthranilate oxygenase antibody; 3 hydroxyanthranilic acid dioxygenase antibody; 3-HAO antibody; 3-hydroxyanthranilate 3,4-dioxygenase antibody; 3-hydroxyanthranilate oxygenase antibody; 3-hydroxyanthranilic acid dioxygenase antibody; 3HAO_HUMAN antibody; haao antibody; HAD antibody; HAO antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human HAAO
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
  • 基因功能参考文献：
    1. Here, the first crystal structure of human 3-HAO with the native iron bound in its active site is presented, together with an additional structure with zinc (a known inhibitor of human 3-HAO) bound in the active site. PMID: 28375145
    2. Methylation status of CIDEA, HAAO and RXFP3 had significant association with microsatellite instability in endometrial tumors. PMID: 20211485
    3. GTF2A1 alone, or GTF2A1 plus HAAO are excellent candidate biomarkers for detecting Ovarian cancer PMID: 19724865
  • 亚细胞定位：
    Cytoplasm, cytosol.
  • 蛋白家族：
    3-HAO family
  • 数据库链接：

    HGNC: 4796

    OMIM: 604521

    KEGG: hsa:23498

    STRING: 9606.ENSP00000294973

    UniGene: Hs.368805