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HNRNPR Antibody

  • 货号：
    CSB-PA010614GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    O43390
  • 基因名：
    HNRNPR
  • 别名：
    FLJ25714 antibody; Heterogeneous nuclear ribonucleoprotein R antibody; hnRNP R antibody; hnRNP-R antibody; HNRNPR antibody; HNRPR antibody; HNRPR_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human HNRNPR
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of ribonucleosomes, which are complexes of at least 20 other different heterogeneous nuclear ribonucleoproteins (hnRNP). hnRNP play an important role in processing of precursor mRNA in the nucleus.
  • 基因功能参考文献：
    1. demonstrated that HNRNPR binds MHC class I mRNAs in their 3' untranslated regions and enhances their stability and their expression; regulation by HNRNPR modulates the cytotoxic activity of NK cell; conclude that HNRNPR acts as a general positive regulator of MHC class I expression PMID: 27194785
    2. SMN is involved in the axonal translocation of hnRNP R and hnRNP R-bound RNA/protein complexes. PMID: 25338097
    3. Data demonstrate that expression levels of hnRNP A1, Q, K, R, and U influence HIV-1 production by persistently infected astrocytes, linking these hnRNPs to HIV replication. PMID: 19808671
    4. Short-term exercise resulted in a significant increase of mRNA expression of genes encoding proteins involved in the formation of precatalytic splisosome: HNRNPR. PMID: 19902070
    5. HNRNPR enhanced transcription from the c-fos promoter. PMID: 19581295
    6. validated occurrence of an unusual TG 3' splice site in intron 7 PMID: 17672918

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  • 亚细胞定位：
    Nucleus. Microsome. Nucleus, nucleoplasm. Cytoplasm.
  • 数据库链接：

    HGNC: 5047

    OMIM: 607201

    KEGG: hsa:10236

    STRING: 9606.ENSP00000363745

    UniGene: Hs.373763