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HOXC9 Antibody

  • 货号：
    CSB-PA010679LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) HOXC9 Polyclonal antibody
  • Uniprot No.：
    P31274
  • 基因名：
    HOXC9
  • 别名：
    Homeo box C9 antibody; Homeobox C9 antibody; Homeobox protein Hox C9 antibody; Homeobox protein Hox-3B antibody; Homeobox protein Hox-C9 antibody; Hox 3B antibody; HOX3 antibody; HOX3B antibody; Hoxc9 antibody; HXC9_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Homeobox protein Hox-C9 protein (18-260AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，HOXC9 Antibody (CSB-PA010679LA01HU)，的标记方式是Non-conjugated。对于HOXC9 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA010679LB01HU HOXC9 Antibody, HRP conjugated ELISA
    FITC CSB-PA010679LC01HU HOXC9 Antibody, FITC conjugated
    Biotin CSB-PA010679LD01HU HOXC9 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
  • 基因功能参考文献：
    1. HOXC9 knockdown inhibited the metastasis and stem cell-like phenotype of GC cells without significant effects on cell proliferation as a direct target of miR-26a. PMID: 30205370
    2. downregulation of HOXC9 releases its transcriptional inhibition of DAPK1, resulting in the activation of the DAPK1-Beclin1 pathway, which induces autophagy in glioblastoma cells PMID: 26582930
    3. HOXC9 and HOXC10 may play an important role in the development of obesity, adverse fat distribution, and subsequent alterations in whole-body metabolism and adipose tissue function. PMID: 26647900
    4. Results provide a set of the essential genes in the miR-193a-3p/HOXC9/DNA damage response/oxidative stress pathway axis as the diagnostic targets for the guided anti-bladder cancer chemotherapy. PMID: 25444900
    5. HOXC9 coordinates diverse cellular processes associated with differentiation by directly activating and repressing the transcription of distinct sets of genes. PMID: 24274069
    6. HoxC9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma. PMID: 23579273
    7. We did not find any potential pathological mutations in the Hoxc9 gene among Chinese patients with congenital heart disease. PMID: 22106857
    8. The data identify HOXC9 as an endothelial cell active transcriptional repressor promoting the resting, antiangiogenic endothelial cell phenotype in an interleukin 8-dependent manner PMID: 21493894
    9. HOXC9 links cell-cycle exit and neuronal differentiation and is a prognostic marker in neuroblastoma. PMID: 21507931
    10. Up-regulation of HOXC9 was detected in a set of 54 astrocytomas of different grades and significantly associated with malignancy. PMID: 17588684
    11. Methylated state of this set of genes may be more specific to the late rather than the early stage of NSCLC. PMID: 19506903

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Abd-B homeobox family
  • 数据库链接：

    HGNC: 5130

    OMIM: 142971

    KEGG: hsa:3225

    STRING: 9606.ENSP00000302836

    UniGene: Hs.658823