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HOXD11 Antibody

  • 货号：
    CSB-PA975571
  • 规格：
    ￥1100
  • 图片：
    • Gel: 10+12%SDS-PAGE, Lysate: 30 μg, Lane: Mouse kidney tissue, Primary antibody: CSB-PA975571(HOXD11 Antibody) at dilution 1/1100, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 60 seconds
  • 其他：

产品详情

  • Uniprot No.：
    P31277
  • 基因名：
    HOXD11
  • 别名：
    Homeo box 4F antibody; Homeo box D11 antibody; Homeobox D11 antibody; Homeobox protein Hox-4F antibody; Homeobox protein Hox-D11 antibody; Hox-4F antibody; HOX4 antibody; HOX4F antibody; HOXD11 antibody; HXD11_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human HOXD11
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    WB 1:1000-1:3000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
  • 基因功能参考文献：
    1. High expression of HOXD11 is associated with laryngeal squamous cell carcinoma. PMID: 27658780
    2. data show no significant difference in HOXD11, HOXD12 & HOXD13 genotype frequencies between the autism spectrum disorder & healthy controls, but one SNP in promoter region of HOXD11 was observed in only 4 patients with ASD PMID: 19540081
    3. In human embryonic stem cell (hESCs)differentiation, a 1.8kb region between HOXD11 and HOXD12 (D11.12) that is associated with PcG proteins was discovered, it shows alteration in nuclease sensitivity as hESCs differentiate. PMID: 20085705
    4. The HOXD11 gene is fused to the NUP98 gene in acute myeloid leukemia with t(2;11)(q31;p15). PMID: 11782354
    5. Our findings do not support the hypothesis that mutations in the HOXD11 coding regions are involved in the pathogenesis of human non-syndromal congenital renal parenchymal malformations. PMID: 19255789

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  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Abd-B homeobox family
  • 数据库链接：

    HGNC: 5134

    OMIM: 142986

    KEGG: hsa:3237

    STRING: 9606.ENSP00000249504

    UniGene: Hs.421136