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HTR3D Antibody

  • 货号:
    CSB-PA008034
  • 规格:
    ¥880
  • 图片:
    • Western Blot analysis of HT-29 cells using SR-3D Polyclonal Antibody
  • 其他:

产品详情

  • Uniprot No.:
    Q70Z44
  • 基因名:
    HTR3D
  • 别名:
    HTR3D; 5-hydroxytryptamine receptor 3D; 5-HT3-D; 5-HT3D; Serotonin receptor 3D
  • 宿主:
    Rabbit
  • 反应种属:
    Human
  • 免疫原:
    Synthesized peptide derived from the N-terminal region of Human SR-3D.
  • 免疫原种属:
    Homo sapiens (Human)
  • 标记方式:
    Non-conjugated
  • 抗体亚型:
    IgG
  • 纯化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式:
    Liquid
  • 应用范围:
    WB, IF, ELISA
  • 推荐稀释比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:200-1:1000
    ELISA 1:10000
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.
  • 基因功能参考文献:
    1. Polymorphism in HTR3D shows differential risks for acute chemotherapy-induced vomiting after anthracycline chemotherapy. PMID: 20602613
  • 亚细胞定位:
    Cell membrane; Multi-pass membrane protein. Note=Presumably retained within the endoplasmic reticulum unless complexed with HTR3A.
  • 蛋白家族:
    Ligand-gated ion channel (TC 1.A.9) family, 5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily, HTR3D sub-subfamily
  • 组织特异性:
    Expressed in liver, as well as fetal and adult colon and kidney.
  • 数据库链接:

    HGNC: 24004

    OMIM: 610122

    KEGG: hsa:200909

    STRING: 9606.ENSP00000371929

    UniGene: Hs.448004