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Hpx Antibody

  • 货号：
    CSB-PA010723LA01RA
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: Hpx antibody at 4.5µg/ml + HepG2 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 52 kDa
      Observed band size: 52 kDa
    • Immunohistochemistry of paraffin-embedded Mouse live tissue using CSB-PA010723LA01RA at dilution of 1:200
    • Immunohistochemistry of paraffin-embedded Human live tissue using CSB-PA010723LA01RA at dilution of 1:200
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Rattus norvegicus (Rat) Hpx Polyclonal antibody
  • Uniprot No.：
    P20059
  • 基因名：
    Hpx
  • 别名：
    Hpx antibody; Hemopexin antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Rat, Human
  • 免疫原：
    Recombinant Rat Hemopexin protein (24-460AA)
  • 免疫原种属：
    Rattus norvegicus (Rat)
  • 标记方式：
    Non-conjugated

    本页面中的产品，Hpx Antibody (CSB-PA010723LA01RA)，的标记方式是Non-conjugated。对于Hpx Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA010723LB01RA Hpx Antibody, HRP conjugated ELISA
    FITC CSB-PA010723LC01RA Hpx Antibody, FITC conjugated
    Biotin CSB-PA010723LD01RA Hpx Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
  • 基因功能参考文献：
    1. Data suggest that apo-hemopexin isolated from plasma exchibits low endogenous levels of tyrosine nitration in the peptide YYCFQGNQFLR in the heme-binding site of human hemopexin, which was similarly nitrated in rabbit and rat hemopexins; heme binding by hemopexin declined as tyrosine nitration proceeded in vitro. PMID: 28596380
    2. Hemopexin was identified as upregulated protein in the small intestine exposed to indomethacin. PMID: 22486875
    3. hemopexin mRNA was low or undetectable in livers of hypophysectomized rats, however, daily treatment with bovine growth hormone for 10 days restored hemopexin mRNA levels PMID: 12850285
    4. intracellular calcium and protein kinase C activation are involved in the regulation of Hpx. PMID: 12850286
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Hemopexin family
  • 组织特异性：
    Expressed by the liver and secreted in plasma.
  • 数据库链接：

    KEGG: rno:58917

    STRING: 10116.ENSRNOP00000024710

    UniGene: Rn.2380