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IARS2 Antibody

  • 货号：
    CSB-PA010933GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9NSE4
  • 基因名：
    IARS2
  • 别名：
    2010002H18Rik antibody; C79125 antibody; EC 6.1.1.5 antibody; FLJ10326 antibody; Iars2 antibody; IleRS antibody; isoleucine tRNA ligase 2, mitochondrial antibody; isoleucine tRNA ligase, mitochondrial antibody; isoleucine tRNA synthetase 2, mitochondrial antibody; Isoleucine--tRNA ligase antibody; isoleucine-tRNA synthetase 2 antibody; isoleucyl tRNA synthetase 2, mitochondrial antibody; Isoleucyl-tRNA synthetase antibody; MGC63429 antibody; mitochondrial antibody; mitochondrial isoleucine tRNA synthetase antibody; rCG_20084 antibody; RGD1311857 antibody; SYIM_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human IARS2
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. IARS2 silencing induced NSCLC cells growth inhibition, cell cycle arrest and promoted cell apoptosis PMID: 26639235
    2. Patients with this very rare mutation present with a myriad of ocular findings, including infantile cataract, neurotrophic keratitis, corneal opacification, and orbital myopathy. PMID: 27078007
    3. The expression of IARS2 gene is different in human colon cancer and surrounding tissues. IARS2 gene is probably a cancer-promoting gene PMID: 26722399
    4. This study is the first report of clinical findings associated with IARS2 mutations. PMID: 25130867
  • 相关疾病：
    Cataracts, growth hormone deficiency, sensory neuropathy, sensorineural hearing loss, and skeletal dysplasia (CAGSSS)
  • 亚细胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    Class-I aminoacyl-tRNA synthetase family
  • 数据库链接：

    HGNC: 29685

    OMIM: 612801

    KEGG: hsa:55699

    STRING: 9606.ENSP00000303279

    UniGene: Hs.262823