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ICAM5 Antibody

  • 货号：
    CSB-PA084116
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA084116(ICAM5 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA084116(ICAM5 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-2: 293T cells, Hela cells, Primary antibody: CSB-PA084116(ICAM5 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
  • 其他：

产品详情

  • Uniprot No.：
    Q9UMF0
  • 基因名：
    ICAM5
  • 别名：
    ICAM5 antibody; TLCN antibody; TLNIntercellular adhesion molecule 5 antibody; ICAM-5 antibody; Telencephalin antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human ICAM5
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2).
  • 基因功能参考文献：
    1. Here the s identify neuron-specific intercellular adhesion molecule 5 (ICAM-5/telencephalin) as a cellular receptor for sialic acid-dependent and -independent entry of enterovirus D68. PMID: 27923705
    2. ICAM5 V301I and rs281439 variants may contribute to the susceptibility of breast cancer. [Meta-analysis] PMID: 23079714
    3. A specific microenvironment facilitating ARF6-mediated mobilization of TLN that contributes to promotion of dendritic spine development. PMID: 22781129
    4. study does not confirm association between ICAM 5 V3001 polymorphism and breast cancer risk PMID: 16434609
    5. ICAM-5 is involved in immune privilege of the brain and acts as an anti-inflammatory agent. PMID: 18223167

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  • 亚细胞定位：
    Membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Immunoglobulin superfamily, ICAM family
  • 组织特异性：
    Expressed on neurons in the most rostral segment of the mammalian brain, the telencephalon.
  • 数据库链接：

    HGNC: 5348

    OMIM: 601852

    KEGG: hsa:7087

    STRING: 9606.ENSP00000221980

    UniGene: Hs.465862