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IDI2 Antibody

  • 货号：
    CSB-PA010995GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9BXS1
  • 基因名：
    IDI2
  • 别名：
    IDI2 antibody; Isopentenyl-diphosphate delta-isomerase 2 antibody; EC 5.3.3.2 antibody; Isopentenyl pyrophosphate isomerase 2 antibody; IPP isomerase 2 antibody; IPPI2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Human IDI2
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
  • 基因功能参考文献：
    1. The present findings suggest that IDI1 and IDI2 may be associated with the production of cholesterol metabolites in neurons, leading to alpha-synuclein aggregation during the process of Lewy body formation. PMID: 25950736
    2. Within the 40-kb region on 10p15.3 subtelomere, which harbours two genes encoding isopentenyl diphosphate isomerase 1 (IDI1) and IDI2, there was found a segmental copy-number gain in a large proportion of sporadic amyotrophic lateral sclerosis patients. PMID: 20955688
    3. IDI2 is expressed at high levels only in skeletal muscle, where it may be involved in the specialized production of isoprenyl diphosphates for the posttranslational modification of proteins. PMID: 14629038
    4. Enzyme kinetic analysis; both isozymes IDI1 and IDI2 are localized to the peroxisome by a PTS1-dependent pathway; data suggest that IDI2 is regulated independently from IDI1, by a mechanism that may involve PPARalpha PMID: 17202134
  • 亚细胞定位：
    Peroxisome.
  • 蛋白家族：
    IPP isomerase type 1 family
  • 组织特异性：
    Muscle-specific expression.
  • 数据库链接：

    HGNC: 23487

    OMIM: 615389

    KEGG: hsa:91734

    STRING: 9606.ENSP00000277517

    UniGene: Hs.591325