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IER2 Antibody

  • 货号：
    CSB-PA01729A0Rb
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) IER2 Polyclonal antibody
  • Uniprot No.：
    Q9BTL4
  • 基因名：
    IER2
  • 别名：
    IER2 antibody; ETR101 antibody; PIP92 antibody; Immediate early response gene 2 protein antibody; Protein ETR101 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Immediate early response gene 2 protein (1-223AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，IER2 Antibody (CSB-PA01729A0Rb)，的标记方式是Non-conjugated。对于IER2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA01729B0Rb IER2 Antibody, HRP conjugated ELISA
    FITC CSB-PA01729C0Rb IER2 Antibody, FITC conjugated
    Biotin CSB-PA01729D0Rb IER2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    DNA-binding protein that seems to act as a transcription factor. Involved in the regulation of neuronal differentiation, acts upon JNK-signaling pathway activation and plays a role in neurite outgrowth in hippocampal cells. May mediate with FIBP FGF-signaling in the establishment of laterality in the embryo. Promotes cell motility, seems to stimulate tumor metastasis.
  • 基因功能参考文献：
    1. IER2 promoted hepatocellular carcinoma cell adhesion and motility by directly increasing ITGB1 expression and subsequently activating the ITGB1FAKSrcpaxillin signal pathway. PMID: 27840969
    2. results from western blot analysis showed that the activity of the focal adhesion kinase (FAK) can be regulated by IER2. PMID: 26260137
    3. ectopic Ier2 expression promoted the motility and invasiveness of poorly metastatic 1AS pancreatic tumor cells in vitro PMID: 22120713
    4. the functioning of ETR101 as a transcriptional activator for the gene ISYNA1 PMID: 19584537
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    IER family
  • 组织特异性：
    Expressed in activated T-cells (at protein level). Expression increases in metastatic tumor cells (at protein level).
  • 数据库链接：

    HGNC: 28871

    KEGG: hsa:9592

    STRING: 9606.ENSP00000292433

    UniGene: Hs.501629