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IFT27 Antibody

  • 货号：
    CSB-PA874822LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA874822LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA874822LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) IFT27 Polyclonal antibody
  • Uniprot No.：
    Q9BW83
  • 基因名：
    IFT27
  • 别名：
    BBS19 antibody; Ift27 antibody; IFT27_HUMAN antibody; Intraflagellar transport 27 antibody; Intraflagellar transport protein 27 homolog antibody; Putative GTP binding protein RAY like antibody; Putative GTP-binding protein RAY-like antibody; Rab like protein 4 antibody; RAB member of RAS oncogene family like 4 antibody; Rab-like protein 4 antibody; RAYL antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Intraflagellar transport protein 27 homolog protein (1-186AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，IFT27 Antibody (CSB-PA874822LA01HU)，的标记方式是Non-conjugated。对于IFT27 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA874822LB01HU IFT27 Antibody, HRP conjugated ELISA
    FITC CSB-PA874822LC01HU IFT27 Antibody, FITC conjugated
    Biotin CSB-PA874822LD01HU IFT27 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Small GTPase-like component of the intraflagellar transport (IFT) complex B that promotes the exit of the BBSome complex from cilia via its interaction with ARL6. Not involved in entry of the BBSome complex into cilium. Prevents aggregation of GTP-free ARL6. Required for hedgehog signaling. Forms a subcomplex within the IFT complex B with IFT25. Its role in intraflagellar transport is mainly seen in tissues rich in ciliated cells such as kidney and testis. Essential for male fertility, spermiogenesis and sperm flagella formation. Plays a role in the early development of the kidney. May be involved in the regulation of ureteric bud initiation.
  • 基因功能参考文献：
    1. Study coupled human genetics with functional validation in zebrafish and identified IFT27 as a novel BBS gene (BBS19). PMID: 24488770
  • 相关疾病：
    Bardet-Biedl syndrome 19 (BBS19)
  • 亚细胞定位：
    Cell projection, cilium. Cytoplasm. Cell projection, cilium, flagellum.
  • 蛋白家族：
    Small GTPase superfamily, Rab family
  • 数据库链接：

    HGNC: 18626

    OMIM: 615870

    KEGG: hsa:11020

    STRING: 9606.ENSP00000393541

    UniGene: Hs.415172