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IGSF11 Antibody

  • 货号：
    CSB-PA011557GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q5DX21
  • 基因名：
    IGSF11
  • 别名：
    IGSF11 antibody; BTIGSF antibody; CXADRL1 antibody; VSIG3 antibody; Immunoglobulin superfamily member 11 antibody; IgSF11 antibody; Brain and testis-specific immunoglobulin superfamily protein antibody; Bt-IGSF antibody; V-set and immunoglobulin domain-containing protein 3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human IGSF11
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth.
  • 基因功能参考文献：
    1. Concerted role for IgSF11 and PSD-95 in the regulation of AMPAR-mediated synaptic transmission and plasticity. PMID: 26595655
    2. Molecular cloning of BT-IgSF which is preferentially expressed by brain and testis PMID: 12207903
    3. cell adhesion-inducing function of BT-IgSF suggests a role of the cell surface molecule in the development/function of the central nervous system and spermatogenesis PMID: 15795899
    4. IGSF11 is a good candidate of cancer-testis antigen. Furthermore, suppression of IGSF11 by siRNA retarded the growth of gastric cancer cells. PMID: 16108831
  • 亚细胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 组织特异性：
    Abundantly expressed in testis and ovary and to a lower extent in brain, kidney and skeletal muscle.
  • 数据库链接：

    HGNC: 16669

    OMIM: 608351

    KEGG: hsa:152404

    STRING: 9606.ENSP00000377370

    UniGene: Hs.112873