Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. INMT Antibody

INMT Antibody

  • 货号：
    CSB-PA011723LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: INMT antibody at 2µg/ml + Mouse lung tissue
      Secondary
      Goat polyclonal to rabbit lgG at 1/15000 dilution
      Predicted band size: 29 kDa
      Observed band size: 29 kDa
    • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA011723LA01HU at dilution of 1:100
    • Immunofluorescence staining of A549 cells with CSB-PA011723LA01HU at 1:150, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) INMT Polyclonal antibody
  • Uniprot No.：
    O95050
  • 基因名：
    INMT
  • 别名：
    Amine N methyltransferase antibody; Amine N-methyltransferase antibody; Aromatic alkylamine N methyltransferase antibody; Aromatic alkylamine N-methyltransferase antibody; Arylamine N methyltransferase antibody; Arylamine N-methyltransferase antibody; Indolamine N-methyltransferase antibody; Indolethylamine N methyltransferase antibody; Indolethylamine N-methyltransferase antibody; Inmt antibody; INMT_HUMAN antibody; nicotine N methyltransferase antibody; TEMT antibody; thioester S methyltransferase like antibody; Thioether S methyltransferase antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Indolethylamine N-methyltransferase protein (1-263AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，INMT Antibody (CSB-PA011723LA01HU)，的标记方式是Non-conjugated。对于INMT Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA011723LB01HU INMT Antibody, HRP conjugated ELISA
    FITC CSB-PA011723LC01HU INMT Antibody, FITC conjugated
    Biotin CSB-PA011723LD01HU INMT Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Functions as thioether S-methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3-methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2-methylthioethylamine, 2-methylthioethanol, methyl-n-propyl sulfide and diethyl sulfide. Plays an important role in the detoxification of selenium compounds. Catalyzes the N-methylation of tryptamine and structurally related compounds.
  • 基因功能参考文献：
    1. study suggests that rs77743549 of INMT may be associated with the risk for Hirschsprung's disease PMID: 26183064
    2. genome-wide association studies in populations in Argentina/Bangladeshi: Three SNPs in INMT (rs6970396, rs1061644, rs4270015) are associated with production of trimethylselenonium (TMSe); urinary Se excretion is up-regulated in TMSe-producing women. PMID: 26537946
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Class I-like SAM-binding methyltransferase superfamily, NNMT/PNMT/TEMT family
  • 组织特异性：
    Widely expressed. The highest levels were in thyroid, adrenal gland, adult and fetal lung. Intermediate levels in heart, placenta, skeletal muscle, testis, small intestine, pancreas, stomach, spinal cord, lymph node and trachea. Very low levels in adult a
  • 数据库链接：

    HGNC: 6069

    OMIM: 604854

    KEGG: hsa:11185

    UniGene: Hs.632629