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  4. INSL4 Antibody

INSL4 Antibody

  • 货号：
    CSB-PA003040
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of HT29 cells using INSL4 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q14641
  • 基因名：
    INSL4
  • 别名：
    early placenta insulin like peptide (EPIL) antibody; Early placenta insulin like peptide A chain antibody; Early placenta insulin like peptide antibody; Early placenta insulin like peptide B chain antibody; Early placenta insulin-like peptide A chain antibody; EPIL antibody; INSL4 antibody; INSL4_HUMAN antibody; insulin like 4 antibody; insulin like 4 (placenta) antibody; Insulin like peptide 4 antibody; Insulin-like peptide 4 antibody; OTTHUMP00000021025 antibody; Placentin antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human INSL4.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, IF, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May play an important role in trophoblast development and in the regulation of bone formation.
  • 基因功能参考文献：
    1. Report decreased INSL4 gene expression in both the invasive and the noninvasive areas of villous trophoblast in patients with placenta accreta. PMID: 23302396
    2. We identified an INSL4 alternatively spliced mRNA species that encodes putative novel INSL4-like peptides. PMID: 12606452
    3. Expression of the INSL4 gene was doubled in the placenta of the growth-restricted twin compared to the normally grown sibling, suggesting that it may be linked to a higher level of apoptosis and loss of cell viability PMID: 15958731
    4. A tight interaction between HER-2 gene and EPIL in invasive breast cancer cells is probable. PMID: 18035692
  • 亚细胞定位：
    Secreted.
  • 蛋白家族：
    Insulin family
  • 组织特异性：
    Expressed in placenta, uterus and in fetal perichondrium. Expression levels were increased in both early placentas and molar pregnancies and were reduced in choriocarcinoma cells.
  • 数据库链接：

    HGNC: 6087

    OMIM: 600910

    KEGG: hsa:3641

    STRING: 9606.ENSP00000239316

    UniGene: Hs.418506