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ISCA2 Antibody

  • 货号：
    CSB-PA769773LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: ISCA2 antibody at 0.4µg/ml + HL60 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 17, 7 kDa
      Observed band size: 17 kDa
    • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA769773LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA769773LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ISCA2 Polyclonal antibody
  • Uniprot No.：
    Q86U28
  • 基因名：
    ISCA2
  • 别名：
    c14_5557 antibody; HESB like domain containing 1 antibody; HESB like domain containing protein 1 antibody; HESB-like domain-containing protein 1 antibody; iron sulfur cluster assembly 2 homolog (S. cerevisiae) antibody; Iron sulfur cluster assembly 2 homolog; mitochondrial antibody; Iron-sulfur cluster assembly 2 homolog; mitochondrial antibody; ISCA2 antibody; ISCA2_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Iron-sulfur cluster assembly 2 homolog, mitochondrial protein (9-154AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，ISCA2 Antibody (CSB-PA769773LA01HU)，的标记方式是Non-conjugated。对于ISCA2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA769773LB01HU ISCA2 Antibody, HRP conjugated ELISA
    FITC CSB-PA769773LC01HU ISCA2 Antibody, FITC conjugated
    Biotin CSB-PA769773LD01HU ISCA2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. May be involved in the binding of an intermediate of Fe/S cluster assembly.
  • 基因功能参考文献：
    1. We identified a homoallelic missense founder mutation in ISCA2 leading to mitochondrial depletion and reduced complex I activity as well as decreased ISCA2, ISCA1 and IBA57 expression in fibroblasts. PMID: 25539947
  • 相关疾病：
    Multiple mitochondrial dysfunctions syndrome 4 (MMDS4)
  • 亚细胞定位：
    Mitochondrion.
  • 蛋白家族：
    HesB/IscA family
  • 数据库链接：

    HGNC: 19857

    OMIM: 615317

    KEGG: hsa:122961

    STRING: 9606.ENSP00000452007

    UniGene: Hs.291079