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ITGB1BP2 Antibody

  • 货号：
    CSB-PA011882GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9UKP3
  • 基因名：
    ITGB1BP2
  • 别名：
    ITGB1BP2 antibody; MSTP015 antibody; Integrin beta-1-binding protein 2 antibody; Melusin antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human ITGB1BP2
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May play a role during maturation and/or organization of muscles cells.
  • 基因功能参考文献：
    1. Studies in mouse show that melusin prevents cardiac dilation during chronic pressure overload by specifically sensing mechanical stress. PMID: 12496958
    2. Identification of a missense mutation in the melusin-encoding ITGB1BP2 gene in a patient with dilated cardiomyopathy PMID: 23124043
    3. The altered melusin pathways and CDC42 parallel the cardiac function progression during cardiac remodeling post-MI. PMID: 21546274
    4. Our analysis revealed an extremely low number of variations in the ITGB1BP2 gene in nearly 1000 hypertensive/cardiopathic and healthy individuals, thus suggesting a high degree of conservation of the melusin gene within the populations analyzed PMID: 20017903
  • 组织特异性：
    Expressed in skeletal and cardiac muscles but not in other tissues.
  • 数据库链接：

    HGNC: 6154

    OMIM: 300332

    KEGG: hsa:26548

    STRING: 9606.ENSP00000362935

    UniGene: Hs.109999