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JAKMIP1 Antibody

  • 货号：
    CSB-PA011933GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q96N16
  • 基因名：
  • 别名：
    FLJ31564 antibody; GABA B receptor binding protein antibody; GABA-B receptor-binding protein antibody; GABABRBP antibody; Jak and microtubule interacting protein 1 antibody; JAKMIP 1 antibody; JAKMIP1 antibody; JAMIP1 antibody; Janus kinase and microtubule interacting protein 1 antibody; Janus kinase and microtubule-interacting protein 1 antibody; JKIP1_HUMAN antibody; Marlin 1 antibody; Marlin-1 antibody; MARLIN1 antibody; Multiple alpha-helices and RNA-linker protein 1 antibody; Multiple coiled coil GABABR1 binding protein antibody; OTTHUMP00000155144 antibody; OTTHUMP00000203209 antibody; OTTHUMP00000203210 antibody; OTTHUMP00000203212 antibody; OTTHUMP00000217225 antibody; OTTHUMP00000217781 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human JAKMIP1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements.
  • 基因功能参考文献：
    1. JAKMIP1 associates with and possibly contributes to the Wnt/beta-catenin pathway activity through its influence on downstream Wnt target proteins, including beta-catenin. PMID: 23481296
    2. Marlin-1 functions to regulate the cellular levels of GABA(B) R2 subunits, which may have significant effects on the production of functional GABA(B) receptor heterodimers PMID: 14718537
    3. Marlin1 has a role in cell polarization, segregation of signaling complexes, and vesicle traffic, some of which may involve Jak tyrosine kinases PMID: 15277531
    4. We have identified four new transcripts of 2975 bp, 1743 bp, 2189 bp and 2420 bp respectively, named Jakmip1B, Jakmip1C, Jakmip1D and Jakmip1E PMID: 17761393
    5. Jakmip1 is a novel effector memory gene that restrains T cell-mediated cytotoxicity. PMID: 18941173

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  • 亚细胞定位：
    Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein. Note=Colocalizes with the microtubule network. Localizes to the cell body and neurites of hippocampal neurons where it accumulates in granules. Localizes to the tail and to a lower extent to the head of sperm cells.
  • 蛋白家族：
    JAKMIP family
  • 组织特异性：
    Predominantly expressed in neural tissues and lymphoid cells (at protein level). Isoform 2, isoform 3 and isoform 4 are specifically expressed in brain and retina. Isoform 1 and isoform 5 are also detected in liver, lung and skeletal muscle. Also detected
  • 数据库链接：

    HGNC: 26460

    OMIM: 611195

    KEGG: hsa:152789

    STRING: 9606.ENSP00000386711

    UniGene: Hs.479066