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KIF26B Antibody

  • 货号：
    CSB-PA642548LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA642548LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA642548LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) KIF26B Polyclonal antibody
  • Uniprot No.：
    Q2KJY2
  • 基因名：
    KIF26B
  • 别名：
    FLJ10157 antibody; KI26B_HUMAN antibody; KIF26B antibody; Kinesin-like protein KIF26B antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Kinesin-like protein KIF26B protein (8-133AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，KIF26B Antibody (CSB-PA642548LA01HU)，的标记方式是Non-conjugated。对于KIF26B Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA642548LB01HU KIF26B Antibody, HRP conjugated ELISA
    FITC CSB-PA642548LC01HU KIF26B Antibody, FITC conjugated
    Biotin CSB-PA642548LD01HU KIF26B Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Essential for embryonic kidney development. Plays an important role in the compact adhesion between mesenchymal cells adjacent to the ureteric buds, possibly by interacting with MYH10. This could lead to the establishment of the basolateral integrity of the mesenchyme and the polarized expression of ITGA8, which maintains the GDNF expression required for further ureteric bud attraction. Although it seems to lack ATPase activity it is constitutively associated with microtubules.
  • 基因功能参考文献：
    1. Upregulation of KIF26B enhanced proliferation and migration of ovarian cancer cells in vitro PMID: 29880787
    2. KIF26B, a novel oncogene regulated by miR-372, promotes proliferation and metastasis through the VEGF pathway in gastric cancer PMID: 28581513
    3. KIF26B plays an important role in colorectal carcinogenesis and functions as a novel prognostic indicator and a potential therapeutic target for CRC. PMID: 25652119
    4. High expression of KIF26B in breast cancer associates with poor prognosis. PMID: 23585914
  • 亚细胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton.
  • 蛋白家族：
    TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, KIF26 subfamily
  • 数据库链接：

    HGNC: 25484

    OMIM: 614026

    KEGG: hsa:55083

    STRING: 9606.ENSP00000385545

    UniGene: Hs.143134