KRT17 Antibody
产品详情
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产品名称:Rabbit anti-Bovine KRT17 Polyclonal antibody
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Uniprot No.:A1L595
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基因名:
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别名:KRT17 antibody; Keratin antibody; type I cytoskeletal 17 antibody; Cytokeratin-17 antibody; CK-17 antibody; Keratin-17 antibody; K17 antibody
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宿主:Rabbit
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反应种属:Bovine
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免疫原:Recombinant Bovine Keratin, type I cytoskeletal 17 protein (1-441AA)
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免疫原种属:Bovine
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标记方式:Non-conjugated
本页面中的产品,KRT17 Antibody (CSB-PA012516LA01BO),的标记方式是Non-conjugated。对于KRT17 Antibody,我们还提供其他标记。见下表:
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:>95%, Protein G purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
产品提供形式:Liquid
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应用范围:ELISA
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Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial 'stem cells'. Acts as a promoter of epithelial proliferation by acting a regulator of immune response in skin: promotes Th1/Th17-dominated immune environment contributing to the development of basaloid skin tumors. May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation.
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亚细胞定位:Cytoplasm.
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蛋白家族:Intermediate filament family
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数据库链接:
KEGG: bta:281889
STRING: 9913.ENSBTAP00000008948
UniGene: Bt.91540
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