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KYAT3 Antibody

  • 货号：
    CSB-PA740996LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA740996LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA740996LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) KYAT3 Polyclonal antibody
  • Uniprot No.：
    Q6YP21
  • 基因名：
    KYAT3
  • 别名：
    CCBL 2 antibody; Cysteine conjugate beta lyase 2 antibody; Cysteine S conjugate beta lyase 2 antibody; Cysteine-S-conjugate beta-lyase 2 antibody; DKFZp547N1117 antibody; DKFZp667D0223 antibody; KAT 3 antibody; KAT III antibody; KAT3 antibody; KAT3_HUMAN antibody; KATIII antibody; kyat3 antibody; Kynurenine aminotransferase 3 antibody; Kynurenine aminotransferase III antibody; Kynurenine oxoglutarate transaminase 3 antibody; Kynurenine oxoglutarate transaminase III antibody; Kynurenine--glyoxylate transaminase antibody; Kynurenine--oxoglutarate transaminase 3 antibody; Kynurenine--oxoglutarate transaminase III antibody; MGC9398 antibody; RBM1 antibody; RBMX L1 antibody; RBMXL 1 antibody; RBMXL1 antibody; RNA binding motif protein X linked like 1 antibody; RP11 82K18.3 antibody; RP4 531M19.2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Kynurenine--oxoglutarate transaminase 3 protein (1-454AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，KYAT3 Antibody (CSB-PA740996LA01HU)，的标记方式是Non-conjugated。对于KYAT3 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA740996LB01HU KYAT3 Antibody, HRP conjugated ELISA
    FITC CSB-PA740996LC01HU KYAT3 Antibody, FITC conjugated
    Biotin CSB-PA740996LD01HU KYAT3 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others. May catalyze the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, serine, cysteine, methionine, histidine, glutamine and asparagine with glyoxylate as an amino group acceptor (in vitro). Has lower activity with 2-oxoglutarate as amino group acceptor (in vitro).
  • 基因功能参考文献：
    1. Immunohistochemical analysis revealed the presence of KAT I, II, and III in all examined corneal sections. PMID: 28706436
    2. human KAT III/CCBL2 possesses cysteine S-conjugate beta-lyase activity, as does mouse KAT II PMID: 25231977
    3. The haplotype of KAT III gene CGCTCT may have effect on the function of this enzyme in formation of kynurenic acid in some patients with major depressive episodes. PMID: 21492941
    4. Using shotgun mass spectrometry, it was found that this protein is differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia. PMID: 19165527
  • 蛋白家族：
    Class-I pyridoxal-phosphate-dependent aminotransferase family
  • 数据库链接：

    HGNC: 33238

    OMIM: 610656

    KEGG: hsa:56267

    STRING: 9606.ENSP00000260508

    UniGene: Hs.481898